| ID | SAVERM_6873
| Type | CDS
|
| From | 8201233
| nt length | 1218
|
| To | 8202450
| aa length | 405
|
| Gene | dfp
| pI | 6.43
|
| Definition | putative phosphopantothenoylcysteine decarboxylase
| M.W (Da) | 42593
|
| Note | coaBC, PF02441: Flavoprotein
| AseI frg. | G2
|
| SignalP v.4.0 | Non-secretory protein | plot
| Category | metabolism of coenzymes & prosthetic groups
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| coel | SCO1477 putative flavoprotein homologue (partial) | 668 | 0.0e+00
|
| sgr | SGR_6057 putative pantothenate metabolism flavoprotein | 709 | 0.0e+00
|
| sam | SAM23877_1529 Coenzyme A biosynthesis bifunctional protein CoaBC | 670 | 0.0e+00
|
| scab | SCAB75291 putative phosphopantothenoylcysteine decarboxylase | 686 | 0.0e+00
|
| sace | SACE_2102 DNA/pantothenate metabolism flavoprotein | 464 | 4.0e-164
|
| nfar | nfa36140 dfp pantothenate metabolism flavoprotein | 475 | 3.4e-135
|
| mtub | gi|15608530 phosphopantothenoylcysteine synthase/decarboxylase [Mycobacterium tuberculosis H37Rv] | 452 | 1.4e-128
|
| cglu | gi|19552816 COG0452:Phosphopantothenoylcysteine synthetase/decarboxylase [Corynebacterium glutamicum] | 401 | 3.3e-113
|
| bsub | BG13388 yloI; similar to pantothenate metabolism flavoprotein | 277 | 9.1e-76
|
| ecoli | gi|49176381 phosphopantothenoylcysteine synthase/decarboxylase [Escherichia coli K12] | 271 | 5.7e-74
|
| paer | PA5320 [gene=dfp] [prot=DNA/pantothenate metabolism flavoprotein] [comment=PA5320] | 260 | 1.8e-70
|
*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;
Pfam search result
| Model | No. | Description | Position (aa) | Score | E-value
|
| DFP | 1 | DNA / pantothenate metabolism flavoprotein | 190-374 | 234.2 | 9.2e-70
|
| Flavoprotein | 1 | Flavoprotein | 10-179 | 142.3 | 9.6e-42
|
BLAST search result (top 10 hits)
| ID | Description | Score | E-value
|
| WP_202498662.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1741 | 0.0e+00 |
| MPY36187.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosphopan...
| 1673 | 0.0e+00 |
| KOX04613.1 | phosphopantothenoylcysteine decarboxylase [Streptomyces sp. NRRL ...
| 1672 | 0.0e+00 |
| WP_075027538.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1672 | 0.0e+00 |
| WP_067366038.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1671 | 0.0e+00 |
| WP_030343820.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1670 | 0.0e+00 |
| WP_053708223.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1670 | 0.0e+00 |
|
| 1668 | 0.0e+00 |
| WP_153544700.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1666 | 0.0e+00 |
| WP_189772810.1 | bifunctional phosphopantothenoylcysteine decarboxylase/phosp...
| 1666 | 0.0e+00 |
PSORT result
| Localization | Certainty | PSORT said
|
| Not Clear | | Seems to have no N-terminal signal seq.
|