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IDSAVERM_7341 TypeCDS
From8757485 nt length1275
To8756211 aa length424
GeneegtA pI5.57
Definitionputative glutamate-cysteine ligase M.W (Da)46123
Notebiosynthetic gene cluster for ergothioneine, PF04107: Glutamate-cysteine ligase family 2(GCS2) AseI frg.D
SignalP v.4.0Non-secretory protein | plot Categorymiscellaneous

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO0910 hypothetical protein6220.0e+00
sgrSGR_695 putative glutamylcysteine synthetase5210.0e+00
samSAM23877_6630 putative glutamate-cysteine ligase6170.0e+00
scabSCAB11211 putative glutamate-cysteine ligase6340.0e+00
saceSACE_3826 glutamate-cysteine ligase2861.0e-93
nfarnfa48870 gshA glutamylcysteine synthetase2285.8e-61
mtubgi|15610840 GLUTAMATE--CYSTEINE LIGASE GSHA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE) [Mycobacterium tuberculosis H37Rv]2171.0e-57

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

GCS21Glutamate-cysteine ligase family 2(GCS2)37-339251.11.3e-74

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_079064735.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17300.0e+00
WP_095851158.1 MULTISPECIES: ergothioneine biosynthesis glutamate--cysteine... 17290.0e+00
WP_181648827.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17210.0e+00
WP_143656407.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17180.0e+00
WP_097287471.1 MULTISPECIES: ergothioneine biosynthesis glutamate--cysteine... 17140.0e+00
WP_079174017.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17120.0e+00
WP_189185585.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17090.0e+00
QIY99911.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [Strep... 17070.0e+00
GGN57744.1 glutamate--cysteine ligase EgtA [Streptomyces albiflavescens] 17060.0e+00
WP_168498601.1 ergothioneine biosynthesis glutamate--cysteine ligase EgtA [... 17060.0e+00

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.2903 Seems to have no N-terminal signal seq.