| ID | SAVERM_937 | Type | CDS |
| From | 1137480 | nt length | 852 |
| To | 1136629 | aa length | 283 |
| Gene | aveD | pI | 5.35 |
| Definition | C5-O-methyltransferase | M.W (Da) | 30113 |
| Note | avermectin gene cluster | AseI frg. | A |
| SignalP v.4.0 | Non-secretory protein | plot | Category | antibiotic production |
| Bacteria* | Reciprocally best hit to | Score | E-value |
| nfar | nfa47690 hypothetical protein | 75 | 5.0e-15 |
| mtub | gi|15610865 POSSIBLE TRANSFERASE [Mycobacterium tuberculosis H37Rv] | 80 | 1.5e-16 |
| bsub | BG12008 ycgJ; hypothetical protein | 61 | 6.6e-11 |
| paer | PA3171 [gene=ubiG] [prot=3-demethylubiquinone-9 3-methyltransferase] [comment=PA3171] | 63 | 2.6e-11 |
| Model | No. | Description | Position (aa) | Score | E-value | |
| Methyltransf_11 | 1 | Methyltransferase domain | 72-170 | 85.7 | 2.4e-24 | |
| Methyltransf_25 | 1 | Methyltransferase domain | 71-166 | 74.3 | 9e-21 | |
| Methyltransf_31 | 1 | Methyltransferase domain | 69-174 | 70.4 | 1.3e-19 | |
| Methyltransf_23 | 1 | Methyltransferase domain | 56-217 | 60.2 | 1.9e-16 | |
| Ubie_methyltran | 1 | ubiE/COQ5 methyltransferase family | 66-172 | 47.7 | 1.1e-12 | |
| Methyltransf_12 | 1 | Methyltransferase domain | 72-168 | 45.1 | 1.2e-11 | |
| CMAS | 1 | Mycolic acid cyclopropane synthetase | 53-176 | 36.1 | 3.8e-09 | |
| Methyltransf_9 | 1 | Protein of unknown function (DUF1698) | 61-170 | 32.0 | 5.4e-08 | |
| Methyltransf_8 | 1 | Hypothetical methyltransferase | 115-176 | 24.2 | 2.3e-05 | |
| Methyltransf_29 | 1 | Putative S-adenosyl-L-methionine-dependent methyltransferase | 59-170 | 21.7 | 5.9e-05 | |
| MetW | 1 | Methionine biosynthesis protein MetW | 68-162 | 22.4 | 7e-05 |
| ID | Description | Score | E-value |
| WP_164397561.1 | methyltransferase domain-containing protein [Streptomyces ha... | 802 | 1.7e-104 |
| AJP00557.1 | methyltransferase [Streptomyces cyaneogriseus subsp. noncyanogenu... | 797 | 9.8e-104 |
| BAF85841.1 | C5-O-methyltransferase [Streptomyces cyaneogriseus subsp. noncya... | 783 | 1.7e-101 |
| WP_089511882.1 | methyltransferase domain-containing protein [Streptomyces sp... | 714 | 4.1e-91 |
| AAR15334.1 | C5-O-methyltransferase [Streptomyces griseochromogenes] | 686 | 6.3e-87 |
| ACL79581.2 | C5-O-methyltransferase [Streptomyces bingchenggensis] | 684 | 1.3e-86 |
| WP_014173390.1 | MULTISPECIES: class I SAM-dependent methyltransferase [Strep... | 682 | 3.4e-86 |
| ADC45587.1 | C5-O-methyltransferase [Streptomyces nanchangensis] | 677 | 1.7e-85 |
| WP_144385395.1 | methyltransferase domain-containing protein [Streptomyces sp... | 654 | 5.5e-82 |
| WP_199894954.1 | class I SAM-dependent methyltransferase [Streptomyces sp. AV... | 649 | 1.3e-81 |
| Localization | Certainty | PSORT said |
| cytoplasm | 0.3912 | Seems to have no N-terminal signal seq. |