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IDSAVERM_942 TypeCDS
From1187750 nt length16599
To1171152 aa length5532
GeneaveA3 pI5.61
Definitiontype I polyketide synthase AVES 3 M.W (Da)575209
Noteavermectin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt3Beta-ketoacyl synthase, N-terminal domain38-288, 1864-2115, 3663-3913897.65.4e-272

Acyl_transf_13Acyl transferase domain603-921, 2425-2714, 4211-4531734.01.8e-221

KR3KR domain1488-1667, 3288-3467, 5085-5264546.99.4e-166

PS-DH3Polyketide synthase dehydratase976-1272, 2797-3082, 4585-4869498.84.3e-150

Ketoacyl-synt_C3Beta-ketoacyl synthase, C-terminal domain296-412, 2123-2240, 3921-4038429.07.7e-131

KAsynt_C_assoc3Ketoacyl-synthetase C-terminal extension415-565, 2243-2379, 4041-4173176.61.6e-52

PP-binding3Phosphopantetheine attachment site1772-1837, 3572-3637, 5369-5434146.42.1e-43

adh_short3short chain dehydrogenase1490-1647, 3290-3447, 5087-524494.26.4e-27

Thiolase_N3Thiolase, N-terminal domain186-243, 2005-2069, 3802-386989.91.6e-25

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_237529128.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 61490.0e+00
WP_127149609.1 type I polyketide synthase [Streptomyces lydicus] >gb 55550.0e+00
BAH02269.1 polyketide synthase [Streptomyces platensis] 46670.0e+00
BAF85843.1 modular polyketide synthase [Streptomyces cyaneogriseus subsp. n... 45760.0e+00
WP_189240897.1 SDR family NAD(P)-dependent oxidoreductase, partial [Planomo... 45400.0e+00
WP_151473860.1 type I polyketide synthase [Streptomyces triticiradicis] >lc... 43190.0e+00
WP_216340188.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 41720.0e+00
AEH09371.1 (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide... 41230.0e+00
WP_053161307.1 type I polyketide synthase [Streptomyces caatingaensis] 39980.0e+00
WP_073780832.1 type I polyketide synthase [Streptomyces sp. MJM1172] 38850.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.2381 Seems to have no N-terminal signal seq.