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IDSAVERM_943 TypeCDS
From1202573 nt length14646
To1187928 aa length4881
GeneaveA4 pI4.74
Definitiontype I polyketide synthase AVES 4 M.W (Da)510316
Noteavermectin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

ketoacyl-synt3Beta-ketoacyl synthase, N-terminal domain34-284, 1591-1841, 2636-2886945.31.4e-286

Acyl_transf_13Acyl transferase domain578-899, 2139-2456, 3263-3599673.54.8e-203

Ketoacyl-synt_C3Beta-ketoacyl synthase, C-terminal domain292-408, 1849-1966, 2894-3011422.96e-129

KR2KR domain1212-1390, 4183-4361360.91.1e-108

PS-DH1Polyketide synthase dehydratase3650-3946195.41.2e-57

PP-binding3Phosphopantetheine attachment site1498-1564, 2541-2606, 4501-4553131.41e-38

KAsynt_C_assoc3Ketoacyl-synthetase C-terminal extension411-504, 1969-2062, 3014-3070123.93.5e-36

Thiolase_N3Thiolase, N-terminal domain176-239, 1746-1795, 2795-284091.93.7e-26

adh_short2short chain dehydrogenase1213-1373, 4184-434483.11.6e-23

Thioesterase1Thioesterase domain4671-478460.42.5e-16

adh_short_C21Enoyl-(Acyl carrier protein) reductase1223-137252.93.3e-14

Epimerase2NAD dependent epimerase/dehydratase family1214-1356, 4185-432452.25.2e-14

Docking1Erythronolide synthase docking2-2640.31.6e-10

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_237529132.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 211780.0e+00
BAF85844.1 modular polyketide synthase [Streptomyces cyaneogriseus subsp. n... 70640.0e+00
ADC45535.1 modular polyketide synthase [Streptomyces nanchangensis] 65990.0e+00
WP_014173329.1 unnamed protein product [Streptomyces bingchenggensis] >gb 59500.0e+00
WP_143675906.1 SDR family NAD(P)-dependent oxidoreductase, partial [Strepto... 59350.0e+00
WP_107418626.1 type I polyketide synthase, partial [Streptomyces glaucinige... 52620.0e+00
WP_147244369.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 51360.0e+00
ARM20279.1 polyketide synthase [Streptomyces sp. 211726] 49620.0e+00
WP_119993600.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces sp.... 49330.0e+00
WP_189175257.1 SDR family NAD(P)-dependent oxidoreductase [Streptomyces las... 49280.0e+00

PSORT result

LocalizationCertaintyPSORT said
membrane0.2869 Seems to have no N-terminal signal seq.