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IDSAVERM_949 TypeCDS
From1208599 nt length678
To1207922 aa length225
GeneaveBV pI9.13
DefinitiondTDP-4-keto-6-deoxyhexose 3,5-epimerase M.W (Da)24663
Noteavermectin gene cluster AseI frg.A
SignalP v.4.0Non-secretory protein | plot Categoryantibiotic production

Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
coelSCO0400 putative epimerase882.0e-22
sgrSGR_629 putative epimerase2193.0e-73
samSAM23877_5598 putative NDP-hexose epimerase1272.0e-37
scabSCAB23531 putative dTDP-4-dehydrorhamnose 3,5-epimerase933.0e-24
saceSACE_6416 dTDP-4-dehydrorhamnose 3,5-epimerase2272.0e-76
nfarnfa2060 rfbC dTDP-6-deoxy-4-ketoglucose epimerase1483.3e-37
mtubgi|15610601 dTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC (dTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (dTDP-L-RHAMNOSE SYNTHETASE) (THYMIDINE DIPHOSPHO-4-KETO-RHAMNOSE 3,5-EPIMERASE) [Mycobacterium tuberculosis H37Rv]1652.0e-42
cglugi|19551582 COG1898:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Corynebacterium glutamicum]573.4e-10
bsubBG14195 spsL; spore coat polysaccharide biosynthesis protein spsL321.5e-02
ecoligi|16129978 dTDP-4,deoxyrhamnose 3,5 epimerase [Escherichia coli K12]952.6e-21
paerPA5164 [gene=rmlC] [prot=dTDP-4-dehydrorhamnose 3,5-epimerase] [comment=PA5164]1147.6e-27

*coel, Streptomyces coelicolor A3(2); sgr, Streptomyces griseus IFO13350; sam, Streptomyces ambofaciens ATCC 23877; scab, Streptomyces scabies 87.22; sace, Saccharopolyspora erythraea NRRL2338; nfar, Nocardia farcinica IFM 10152; mtub, Mycobacterium tuberculosis H37Rv; cglu, Corynebacterium glutamicum; bsub, Bacillus subtilis; ecoli, Escherichia coli K-12; paer, Pseudomonas aeruginosa;

Pfam search result



ModelNo.DescriptionPosition (aa)ScoreE-value

dTDP_sugar_isom1dTDP-4-dehydrorhamnose 3,5-epimerase34-204182.83.7e-54

BLAST search result (top 10 hits)

ID DescriptionScoreE-value
WP_033324722.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6381.7e-81
WP_103830973.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6372.1e-81
MYV49601.1 dTDP-4-keto-6-deoxy-D-glucose epimerase [Streptomyces sp. SID2888... 6283.8e-80
WP_136741520.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6205.9e-79
WP_067003642.1 dTDP-4-dehydrorhamnose 3,5-epimerase [Streptomyces cellostat... 6181.5e-78
WP_067136897.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6163.5e-78
WP_026120727.1 dTDP-4-dehydrorhamnose 3,5-epimerase [Nocardiopsis potens] 6041.6e-76
WP_011113127.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6016.5e-76
WP_182790363.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein [Strepto... 6007.8e-76
WP_038518213.1 MULTISPECIES: dTDP-4-dehydrorhamnose 3,5-epimerase [Amycolat... 6008.3e-76

PSORT result

LocalizationCertaintyPSORT said
cytoplasm0.2755 Seems to have no N-terminal signal seq.